Leucovorin Calcium Tablets Usp In Pakistan

Leucovorin Calcium Tablets is a form of vitamin B. It works by protecting healthy cells from the toxic effects of methotrexate (anticancer medicine) while allowing it to enter and kill the cancer cells.Unlike folic acid, folinic acid is the active, reduced form of folate that does not require enzymatic conversion in the body. It is primarily used in combination with chemotherapy medicines such as methotrexate and fluorouracil (5-FU) to enhance efficacy and reduce toxicity.

Uses

Reduces toxic effects of folic acid antagonists (e.g., methotrexate)

Adjunct therapy with 5-fluorouracil in cancer treatment

Treatment of folate-deficiency–related megaloblastic anemia

Supportive therapy when folic acid absorption or metabolism is impaired

How It Works

Leucovorin supplies the body with active folate, allowing normal DNA synthesis and cell repair to continue even in the presence of folate-blocking drugs. This helps protect healthy cells while maintaining treatment effectiveness.

Indications and Usage: 

Leucovorin Calcium Tablets is used to prevent the harmful effects of methotrexate (anticancer medicine). It is also used in the treatment of methotrexate overdose. It is a form of vitamin B that is given after 24 hours of methotrexate administration. This makes sure that methotrexate has achieved its anti-cancer effects and also, Leucorin Tablet will prevent the other side effects such as anemia.

Leucovorin Calcium Tablets can be taken with or without food. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects.